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Synthesis, Molecular Docking and Antimicrobial Activities of 3-Formyl-2- (1H)quinolinone Schiff Base Derivatives and 3-(((3-Acetylphenyl)imino)- methyl)quinolin-2-(1H)-one Chalcone Derivatives

Abstract
Some of Schiff base derivatives were separated by condensing 3-formyl-2-quinolinone with various primary amine derivatives in ethanol, in which water is expelled. Moreover, substituted acryloylphenyliminomethylquinolinone chalcone derivatives were prepared by the process of condensation reaction of aldehyde derivatives with 3-acetylphenylquinolinone in dilute solution of ethanolic sodium hydroxide...
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Keywords
Chalcone
Chemistry
Malononitrile
Thiourea
Phenylhydrazine
Antimicrobial
Schiff base
Aldehyde
Thio-
Organic chemistry
Ethanol
Claisen condensation
Condensation reaction
Sodium hydroxide
Amine gas treating
Isatin
Medicinal chemistry
Stereochemistry
Catalysis
Sustainable Development Goals (SDG)
Clean water and sanitation

2020
Article

Open Access

2-Y Citation Average

0.712

Language
Country

pdf file

Synthesis, Molecular Docking and Antimicrobial Activities of 3-Formyl-2- (1H)quinolinone Schiff Base Derivatives and 3-(((3-Acetylphenyl)imino)- methyl)quinolin-2-(1H)-one Chalcone Derivatives
pdf file

Synthesis, Molecular Docking and Antimicrobial Activities of 3-Formyl-2- (1H)quinolinone Schiff Base Derivatives and 3-(((3-Acetylphenyl)imino)- methyl)quinolin-2-(1H)-one Chalcone Derivatives

Abstract
Some of Schiff base derivatives were separated by condensing 3-formyl-2-quinolinone with various primary amine derivatives in ethanol, in which water is expelled. Moreover, substituted acryloylphenyliminomethylquinolinone chalcone derivatives were prepared by the process of condensation reaction of aldehyde derivatives with 3-acetylphenylquinolinone in dilute solution of ethanolic sodium hydroxide...
View PDF
Keywords
Chalcone
Chemistry
Malononitrile
Thiourea
Phenylhydrazine
Antimicrobial
Schiff base
Aldehyde
Thio-
Organic chemistry
Ethanol
Claisen condensation
Condensation reaction
Sodium hydroxide
Amine gas treating
Isatin
Medicinal chemistry
Stereochemistry
Catalysis
Sustainable Development Goals (SDG)
Clean water and sanitation

2020
Article

Open Access

2-Y Citation Average

0.712

Language
Country

pdf file