This research was designed to evaluate the effect of resin infiltration material (Icon) and remineralizing agents casein phosphopeptide- amorphous calcium phosphate (CPP-ACP) and Nano hydroxyl apatite (n-HA) on surface roughness and microhardness of enamel white spot lesion. A total number of 120 sound non-carious human anterior teeth were collected. The labial surfaces of all specimens are treate...