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Synthesis, characterization and cytotoxic study of 2-hydroxy benzothiazole incorporated 1,3,4-oxadiazole derivatives

Abstract
A series of fifteen 1, 3, 4-oxadiazoles derived from 2-hydroxy benzothiazole have been synthesized and screened for the anticancer activity. Different aromatic acids were used for this library for generating structure activity relationship. The in vitro cytotoxicity was done against MCF-7 breast cancer cells. The synthesized compounds showed variable cytotoxic effects. Four compounds showed potent...
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Keywords
Benzothiazole
Oxadiazole
Characterization (materials science)
Chemistry
Combinatorial chemistry
Organic chemistry
Materials science
Nanotechnology
Sustainable Development Goals (SDG)
Good health and well-being


pdf file

Synthesis, characterization and cytotoxic study of 2-hydroxy benzothiazole incorporated 1,3,4-oxadiazole derivatives
pdf file

Synthesis, characterization and cytotoxic study of 2-hydroxy benzothiazole incorporated 1,3,4-oxadiazole derivatives

Abstract
A series of fifteen 1, 3, 4-oxadiazoles derived from 2-hydroxy benzothiazole have been synthesized and screened for the anticancer activity. Different aromatic acids were used for this library for generating structure activity relationship. The in vitro cytotoxicity was done against MCF-7 breast cancer cells. The synthesized compounds showed variable cytotoxic effects. Four compounds showed potent...
View PDF
Keywords
Benzothiazole
Oxadiazole
Characterization (materials science)
Chemistry
Combinatorial chemistry
Organic chemistry
Materials science
Nanotechnology
Sustainable Development Goals (SDG)
Good health and well-being


pdf file