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Ameliorating Effect of Alpha-lipoic Acid on Methotrexate-induced Histological and Biochemical Changes in The Lung of Adult Albino Rat

Abstract
Background: Owing to its antioxidant, anti-inflammatory and anti-fibrotic properties, alpha-lipoic acid (ALA) has been evaluated in a diversity of degenerative diseases and experimental toxicological studies.Aim of the Work: This study was performed to assess the ability of ALA to reverse the histological and biochemical alterations that take place in the rat lungs after exposure to methotrexate.M...
Keywords
Methotrexate
Malondialdehyde
Superoxide dismutase
Glutathione
Saline
Pharmacology
Distilled water
Alpha-Lipoic Acid
Antioxidant
Lung
Lipoic acid
Catalase
Medicine
Chemistry
Pathology
Internal medicine
Biochemistry
Enzyme
Chromatography
Sustainable Development Goals (SDG)
Clean water and sanitation


pdf file

Ameliorating Effect of Alpha-lipoic Acid on Methotrexate-induced Histological and Biochemical Changes in The Lung of Adult Albino Rat
pdf file

Ameliorating Effect of Alpha-lipoic Acid on Methotrexate-induced Histological and Biochemical Changes in The Lung of Adult Albino Rat

Abstract
Background: Owing to its antioxidant, anti-inflammatory and anti-fibrotic properties, alpha-lipoic acid (ALA) has been evaluated in a diversity of degenerative diseases and experimental toxicological studies.Aim of the Work: This study was performed to assess the ability of ALA to reverse the histological and biochemical alterations that take place in the rat lungs after exposure to methotrexate.M...
Keywords
Methotrexate
Malondialdehyde
Superoxide dismutase
Glutathione
Saline
Pharmacology
Distilled water
Alpha-Lipoic Acid
Antioxidant
Lung
Lipoic acid
Catalase
Medicine
Chemistry
Pathology
Internal medicine
Biochemistry
Enzyme
Chromatography
Sustainable Development Goals (SDG)
Clean water and sanitation


pdf file