T hIs study aimed to synthesize silver nanoparticles (AgNPs) using Chenopodium murale extract (CME), to evaluate the antioxidant activity of the Chenopodium murale essential oil (CMEO) and the protective role against nephrotoxicity of AgNPs.seven groups of female sprague-Dawley rats were treated orally for 21 days included the control group, AgNPstreated groups (25 or 50 mg/kg b.w), CMEO-treated g...