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Design, Synthesis and Antibacterial Study of New Agents Having 4-Thiazolidinone Pharmacophore

Abstract
A new series of compounds containing 4-thiazolidinone pharmacophore 5(a-d) have been synthesized. The chemical structure of the intermediate and final compounds was characterized and confirmed by using FT-IR and 1H-NMR spectroscopy. All final compounds were tested against Gram-positive and Gram-negative bacteria using a well-diffusion technique for their ability as antimicrobial agents. The 5b and...
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Keywords
Pharmacophore
Combinatorial chemistry
Chemistry
Computer science
Stereochemistry


pdf file

Design, Synthesis and Antibacterial Study of New Agents Having 4-Thiazolidinone Pharmacophore
pdf file

Design, Synthesis and Antibacterial Study of New Agents Having 4-Thiazolidinone Pharmacophore

Abstract
A new series of compounds containing 4-thiazolidinone pharmacophore 5(a-d) have been synthesized. The chemical structure of the intermediate and final compounds was characterized and confirmed by using FT-IR and 1H-NMR spectroscopy. All final compounds were tested against Gram-positive and Gram-negative bacteria using a well-diffusion technique for their ability as antimicrobial agents. The 5b and...
View PDF
Keywords
Pharmacophore
Combinatorial chemistry
Chemistry
Computer science
Stereochemistry


pdf file