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Eco-friendly synthesis, docking study, pharmacokinetics studies, and anti-proliferative evaluation of pyrimidine derivatives as dual Topoisomerase II and HSP90 inhibitors

Egyptian Journal of Chemistry

Eman S. Tantawy, Wesam S. Shehab, Omnia M. Abo Elenin, Mohamed G. Assy, Doaa A. Elsayed

Citations:

2

Keywords
Pyrimidine
Docking (animal)
Chemistry
Topoisomerase
Pharmacokinetics
Pharmacology
Hsp90
Combinatorial chemistry
Stereochemistry
Biochemistry
Enzyme
Biology
Medicine
Gene
Heat shock protein
Nursing
2025
Article
2-Y Citation Average

0.712

DOI

https://doi.org/10.21608/ejchem.2025.357210.11244

Language

en

Eco-friendly synthesis, docking study, pharmacokinetics studies, and anti-proliferative evaluation of pyrimidine derivatives as dual Topoisomerase II and HSP90 inhibitors

Eco-friendly synthesis, docking study, pharmacokinetics studies, and anti-proliferative evaluation of pyrimidine derivatives as dual Topoisomerase II and HSP90 inhibitors

Egyptian Journal of Chemistry

Eman S. Tantawy, Wesam S. Shehab, Omnia M. Abo Elenin, Mohamed G. Assy, Doaa A. Elsayed

Citations:

2

Keywords
Pyrimidine
Docking (animal)
Chemistry
Topoisomerase
Pharmacokinetics
Pharmacology
Hsp90
Combinatorial chemistry
Stereochemistry
Biochemistry
Enzyme
Biology
Medicine
Gene
Heat shock protein
Nursing
2025
Article
2-Y Citation Average

0.712

DOI

https://doi.org/10.21608/ejchem.2025.357210.11244

Language

en