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The Possible Protective Role of Ginger Extract Versus Vitamin E Against Simvastatin-Induced Skeletal Myotoxicity in Adult Male Albino Rats: Histological, Physiological and Biochemical Study

Abstract
Introduction:Statins are group of drugs used to reduce total and low density lipoprotein (LDL)-cholesterol level and to reduce the morbidity and mortality of cardiovascular diseases.Meanwhile, induced skeletal muscle-specific mitochondrial impairment, oxidative stress and myotoxicity are serious side effects .Vitamin E and ginger extract are well known potent antioxidants.Aim: To study the possibl...
Keywords
Simvastatin
Skeletal muscle
Vitamin E
Medicine
Vitamin
Oxidative stress
Statin
Internal medicine
Endocrinology
Concomitant
Myotoxin
Pharmacology
Antioxidant
Biology
Biochemistry
Enzyme
Phospholipase A2
Sustainable Development Goals (SDG)
Good health and well-being


pdf file

The Possible Protective Role of Ginger Extract Versus Vitamin E Against Simvastatin-Induced Skeletal Myotoxicity in Adult Male Albino Rats: Histological, Physiological and Biochemical Study
pdf file

The Possible Protective Role of Ginger Extract Versus Vitamin E Against Simvastatin-Induced Skeletal Myotoxicity in Adult Male Albino Rats: Histological, Physiological and Biochemical Study

Abstract
Introduction:Statins are group of drugs used to reduce total and low density lipoprotein (LDL)-cholesterol level and to reduce the morbidity and mortality of cardiovascular diseases.Meanwhile, induced skeletal muscle-specific mitochondrial impairment, oxidative stress and myotoxicity are serious side effects .Vitamin E and ginger extract are well known potent antioxidants.Aim: To study the possibl...
Keywords
Simvastatin
Skeletal muscle
Vitamin E
Medicine
Vitamin
Oxidative stress
Statin
Internal medicine
Endocrinology
Concomitant
Myotoxin
Pharmacology
Antioxidant
Biology
Biochemistry
Enzyme
Phospholipase A2
Sustainable Development Goals (SDG)
Good health and well-being


pdf file