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The Possible Role of Propolis in Ameliorating Paclitaxel-Induced Peripheral Neuropathy in Sciatic Nerve of Adult Male Albino Rats

Abstract
Background: Paclitaxel is a neurotoxic chemotherapeutic agent. The sensorimotor peripheral neuropathy is a serious dose limiting complication of paclitaxel therapy. Propolis is a natural honeybee product collected from plants. It has broad biological and pharmacological activities and a proposed neuroprotective role.Aim: To assess the possible protective role of propolis on paclitaxel-induced peri...
Keywords
Propolis
Paclitaxel
Sciatic nerve
Peripheral neuropathy
CD68
Medicine
Immunohistochemistry
Myelin
Pathology
Pharmacology
Chemotherapy
Anatomy
Internal medicine
Endocrinology
Central nervous system
Traditional medicine
Diabetes mellitus



The Possible Role of Propolis in Ameliorating Paclitaxel-Induced Peripheral Neuropathy in Sciatic Nerve of Adult Male Albino Rats

The Possible Role of Propolis in Ameliorating Paclitaxel-Induced Peripheral Neuropathy in Sciatic Nerve of Adult Male Albino Rats

Abstract
Background: Paclitaxel is a neurotoxic chemotherapeutic agent. The sensorimotor peripheral neuropathy is a serious dose limiting complication of paclitaxel therapy. Propolis is a natural honeybee product collected from plants. It has broad biological and pharmacological activities and a proposed neuroprotective role.Aim: To assess the possible protective role of propolis on paclitaxel-induced peri...
Keywords
Propolis
Paclitaxel
Sciatic nerve
Peripheral neuropathy
CD68
Medicine
Immunohistochemistry
Myelin
Pathology
Pharmacology
Chemotherapy
Anatomy
Internal medicine
Endocrinology
Central nervous system
Traditional medicine
Diabetes mellitus