Effect of Peperomia pellucida L. Kunt Extract in Inhibiting the Increase of Alanine Aminotransferase Enzyme and Changes in Liver Histopathology of Alcohol-Fed Wistar Male Rats (Rattus norvegicus)

Marhaen Hardjo, Laras Puspita Taib, Surahmat Surahmat, Gita Vita Soraya, Muhammad Husni Cangara, Rosdiana Natzir

Abstract

Alcoholic beverages are an addictive substance whose use causes many negative effects on health, such as on the liver, causing an increase in the enzyme alanine aminotransferase (ALT) in the blood. The aim of this study was to investigate the effect of ethyl acetate extract of Peperomia p. L. Kunt leaves and stems in inhibiting the increase of alanine aminotransferase (ALT) enzyme and liver histop...

Keywords

Alanine aminotransferase

Histopathology

Enzyme

Alcohol

Alanine

Biology

Alanine transaminase

Endocrinology

Chemistry

Internal medicine

Pharmacology

Biochemistry

Medicine

Pathology

Amino acid

Sustainable Development Goals (SDG)

Zero hunger

2024

Article

Institution

1. Biomedical Science, Postgraduate Program, Hasanuddin University, Indonesia 2. Biochemistry Department, Medical Faculty, Hasanuddin University, Indonesia

2-Y Citation Average

0.712

DOI

https://doi.org/10.21608/ejchem.2024.305985.10063

Language

en

Country

Indonesia

Effect of Peperomia pellucida L. Kunt Extract in Inhibiting the Increase of Alanine Aminotransferase Enzyme and Changes in Liver Histopathology of Alcohol-Fed Wistar Male Rats (Rattus norvegicus)

Egyptian Journal of Chemistry

Marhaen Hardjo, Laras Puspita Taib, Surahmat Surahmat, Gita Vita Soraya, Muhammad Husni Cangara, Rosdiana Natzir

Abstract

Alcoholic beverages are an addictive substance whose use causes many negative effects on health, such as on the liver, causing an increase in the enzyme alanine aminotransferase (ALT) in the blood. The aim of this study was to investigate the effect of ethyl acetate extract of Peperomia p. L. Kunt leaves and stems in inhibiting the increase of alanine aminotransferase (ALT) enzyme and liver histop...