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Synthesis, Characterization, and Bioactivity of a Tridentate Nitrogen–Sulfur Schiff Base Derived from Carbothioamide and Its (Fe, Co, Cu, Cd) Metal Complexes: DFT, Molecular Docking, and Biomedical Applications

Egyptian Journal of Chemistry

mohammed mahmoud ahmed, Rifaat H Hilal, Mohammad Saied Mansour, Ahmed Abdou El-Sherif

Citations:

3

Abstract

This investigation presents a detailed examination of transition metal complexes derived from a recently synthesized Carbothioamide Schiff Base Ligand, denoted as (Z)-2-((E)-1-(2-(4-chlorophenyl)hydrazineylidene)propan-2-ylidene)-N-phenylhydrazine-1-carbothioamide or (ZHC), known for its biological potency. The synthesis involved condensation of (E)-1-(2-(4-chlorophenyl)hydrazineylidene)propan-2-o...

Keywords

Schiff base

Sulfur

Chemistry

Metal

Docking (animal)

Nitrogen

Stereochemistry

Combinatorial chemistry

Organic chemistry

Medicine

Nursing

Sustainable Development Goals (SDG)

Clean water and sanitation

2024

Article

Institution

Faculty of science, Cairo university

2-Y Citation Average

0.712

DOI

https://doi.org/10.21608/ejchem.2024.311195.10172

Language

Country

Synthesis, Characterization, and Bioactivity of a Tridentate Nitrogen–Sulfur Schiff Base Derived from Carbothioamide and Its (Fe, Co, Cu, Cd) Metal Complexes: DFT, Molecular Docking, and Biomedical Applications

Synthesis, Characterization, and Bioactivity of a Tridentate Nitrogen–Sulfur Schiff Base Derived from Carbothioamide and Its (Fe, Co, Cu, Cd) Metal Complexes: DFT, Molecular Docking, and Biomedical Applications

Egyptian Journal of Chemistry

mohammed mahmoud ahmed, Rifaat H Hilal, Mohammad Saied Mansour, Ahmed Abdou El-Sherif

Citations:

3

Abstract

This investigation presents a detailed examination of transition metal complexes derived from a recently synthesized Carbothioamide Schiff Base Ligand, denoted as (Z)-2-((E)-1-(2-(4-chlorophenyl)hydrazineylidene)propan-2-ylidene)-N-phenylhydrazine-1-carbothioamide or (ZHC), known for its biological potency. The synthesis involved condensation of (E)-1-(2-(4-chlorophenyl)hydrazineylidene)propan-2-o...

Keywords

Schiff base

Sulfur

Chemistry

Metal

Docking (animal)

Nitrogen

Stereochemistry

Combinatorial chemistry

Organic chemistry

Medicine

Nursing

Sustainable Development Goals (SDG)

Clean water and sanitation

2024

Article

Institution

Faculty of science, Cairo university

2-Y Citation Average

0.712

DOI

https://doi.org/10.21608/ejchem.2024.311195.10172

Language

Country