Integrating in-vitro experiments and in-silico approaches identified antiviral activity of black mulberry (Morus nigra) as a potential treatment option for SARS-CoV-2

Abstract

SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), belongs to β-coronavirus, responsible of coronavirus disease-2019 pandemic (COVID-19), claiming roughly 4.9 million lives worldwide. Currently, there's no specific therapy for the disease. Infection begins with the Spike glycoprotein binding to ACE2 (angiotensin-converting enzyme 2) receptors. The study aimed to identify potential inhib...

Keywords

In silico

In vitro

Computational biology

Virology

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Coronavirus disease 2019 (COVID-19)

Traditional medicine

Biology

Chemistry

Medicine

Biochemistry

Pathology

Disease

Gene

Infectious disease (medical specialty)

Sustainable Development Goals (SDG)

Good health and well-being

2024

Article

Institution

Department of Biological Sciences, faculty of Science, King Abdulaziz University, Jeddah. Princess Dr. Najla Bint Saud Al-Saud Center for Excellence Research in Biotechnology, King Abdul-Aziz University, Jeddah 21589, Saudi Arabia.,

King Abdulaziz University

2-Y Citation Average

0.712

DOI

https://doi.org/10.21608/ejchem.2024.301621.9949

Language

en

Country

Saudi Arabia

Integrating in-vitro experiments and in-silico approaches identified antiviral activity of black mulberry (Morus nigra) as a potential treatment option for SARS-CoV-2

Egyptian Journal of Chemistry

Thamer Ahmad Bouback

Abstract

SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), belongs to β-coronavirus, responsible of coronavirus disease-2019 pandemic (COVID-19), claiming roughly 4.9 million lives worldwide. Currently, there's no specific therapy for the disease. Infection begins with the Spike glycoprotein binding to ACE2 (angiotensin-converting enzyme 2) receptors. The study aimed to identify potential inhib...