Evaluation of serum levels of Interleukin -1 and Tumor Necrosis Alpha (TNF-α) and their nucleotide polymorphisms in patients with chronic rhinosinusitis.

Microbes and Infectious Diseases /Microbes and Infectious Diseases

Abdelhakim Fouad Ghallab, Mohamed Goda Elnems, Rasha Abd Elhamid Elsayed, Mostafa Gomaa Sobhey, Eslam Farid Abu Shady

Abstract

Objectives: To evaluate interleukin-1 and TNF- α serum levels and their single nucleotide gene polymorphisms (SNPs) association in patients with chronic rhinosinusitis. Methods: A case-control study performed between June 2022 and March 2023 at Benha University Hospitals, Benha, Egypt. 50 patients with chronic rhinosinusitis (CRS) with nasal polyps (Group 1), 50 patients with CRS without nasal pol...

Keywords

Tumor necrosis factor alpha

Chronic rhinosinusitis

Single-nucleotide polymorphism

Medicine

Immunology

Interleukin

Nucleotide

Alpha (finance)

Tumor necrosis factors

Internal medicine

Genotype

Biology

Cytokine

Gene

Genetics

Surgery

Construct validity

Patient satisfaction

Sustainable Development Goals (SDG)

Good health and well-being

2024

Article

Open Access

Institution

Otorhinolaryngology Department, Faculty of Medicine, Benha University, Benha, Egypt

2-Y Citation Average

0.484

DOI

https://doi.org/10.21608/mid.2024.306823.2100

Language

en

Country

Egypt