Genetic Variants of Interleukin-18 Promoter Gene in Coronary Artery Disease

Lamiaa Mageed, Ibrahim H. Borai, Nahla S. Hassan, Olfat Shaker, Esmat Ashour, Mohammed El Badrawy, Olfat M. Fawzi

Citations:

1

References:

24

Abstract

H EART disease is impacted by ecological and inherited factors.Interleukin-18 (IL-18) is a pro-inflammatory cytokine that stimulates the immune reaction and induces the formation of atherosclerotic plaques.The aim of this study was to determine the relation between IL-18 promoter variants at (607C/A) and (137G/C) sites and coronary artery disease (CAD).A sum of one hundred and twenty Egyptian pati...

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Keywords

Coronary artery disease

Genotyping

Promoter

Genotype

Interleukin 18

Gene

Primer (cosmetics)

Biology

Pathogenesis

Allele

Immunology

Single-nucleotide polymorphism

Genetics

Disease

Cytokine

Medicine

Internal medicine

Gene expression

Chemistry

Organic chemistry

Sustainable Development Goals (SDG)

Good health and well-being

2017

Article

Open Access

Institution

Biochemistry Department, Genetic Engineering and Biotechnology Division, National Research Centre (NRC), Giza-Egypt,

Biochemistry Department, Faculty of Science, Ain Shams University, Cairo, Egypt,

Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University,

The National Heart Institute, Giza, Egypt

2-Y Citation Average

0.712

DOI

https://doi.org/10.21608/ejchem.2017.1337.1085

Language

en

Country

Egypt