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In vitro activity of ceftazidime-avibactam in combination with aztreonam against carbapenem resistant Enterobacterales isolated from intensive care units

Abstract
Background : Carbapenem-resistant (CR) Enterobacterales are established causes of serious healthcare-associated infections. Development of new β-lactam/β-lactamase inhibitors was a breakthrough, but effective antibiotic treatment for metallo-β-lactamase (MBL) producers remained an unmet need. Ceftazidime-avibactam (CZA) combination with aztreonam (ATM) is an emerging option to combat these bugs. A...
Keywords
Aztreonam
Ceftazidime/avibactam
Ceftazidime
Avibactam
Carbapenem
Microbiology
Medicine
Antibiotics
Drug resistance
Antibiotic resistance
Biology
Imipenem
Bacteria
Pseudomonas aeruginosa
Genetics
Sustainable Development Goals (SDG)
Zero hunger



In vitro activity of ceftazidime-avibactam in combination with aztreonam against carbapenem resistant Enterobacterales isolated from intensive care units

In vitro activity of ceftazidime-avibactam in combination with aztreonam against carbapenem resistant Enterobacterales isolated from intensive care units

Abstract
Background : Carbapenem-resistant (CR) Enterobacterales are established causes of serious healthcare-associated infections. Development of new β-lactam/β-lactamase inhibitors was a breakthrough, but effective antibiotic treatment for metallo-β-lactamase (MBL) producers remained an unmet need. Ceftazidime-avibactam (CZA) combination with aztreonam (ATM) is an emerging option to combat these bugs. A...
Keywords
Aztreonam
Ceftazidime/avibactam
Ceftazidime
Avibactam
Carbapenem
Microbiology
Medicine
Antibiotics
Drug resistance
Antibiotic resistance
Biology
Imipenem
Bacteria
Pseudomonas aeruginosa
Genetics
Sustainable Development Goals (SDG)
Zero hunger