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Transformation mediated transfer of Extended Spectrum Beta lactamases (ESBLs) and Sul 1 genes obtained from trimethoprim-sulfamethoxazole resistant (TSR) Escherichia coli and Pseudomonas aeruginosa clinical isolates

Abstract
Background: Plasmid mediated Multi-Drug Resistant (MDR) Sul and ESBL resistance genes are major threats due to their ability to be transferred horizontally in any environment. In this study, the prevalence of Sul1 gene and ESBL genes (blaCTX-M, blaTEM or blaSHV) in E. coli and P. aeruginosa and their capacity to transfer resistance through transformation were determined. Methods: Ninety-two TSR is...
Keywords
Pseudomonas aeruginosa
Microbiology
Plasmid
Biology
Cephalosporin
Sulfamethoxazole
Transformation (genetics)
Multiple drug resistance
Escherichia coli
Genotype
Beta-lactamase
Antibiotic resistance
Antimicrobial
Gene
Amoxicillin
Clavulanic acid
Antibiotics
Bacteria
Genetics
Sustainable Development Goals (SDG)
Zero hunger



Transformation mediated transfer of Extended Spectrum Beta lactamases (ESBLs) and Sul 1 genes obtained from trimethoprim-sulfamethoxazole resistant (TSR) Escherichia coli and Pseudomonas aeruginosa clinical isolates

Transformation mediated transfer of Extended Spectrum Beta lactamases (ESBLs) and Sul 1 genes obtained from trimethoprim-sulfamethoxazole resistant (TSR) Escherichia coli and Pseudomonas aeruginosa clinical isolates

Abstract
Background: Plasmid mediated Multi-Drug Resistant (MDR) Sul and ESBL resistance genes are major threats due to their ability to be transferred horizontally in any environment. In this study, the prevalence of Sul1 gene and ESBL genes (blaCTX-M, blaTEM or blaSHV) in E. coli and P. aeruginosa and their capacity to transfer resistance through transformation were determined. Methods: Ninety-two TSR is...
Keywords
Pseudomonas aeruginosa
Microbiology
Plasmid
Biology
Cephalosporin
Sulfamethoxazole
Transformation (genetics)
Multiple drug resistance
Escherichia coli
Genotype
Beta-lactamase
Antibiotic resistance
Antimicrobial
Gene
Amoxicillin
Clavulanic acid
Antibiotics
Bacteria
Genetics
Sustainable Development Goals (SDG)
Zero hunger