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Ceftolozane-tazobactam, ceftazidime-avibactam and ceftazidime-avibactam plus aztreonam combination: Upcoming hope for hospital-acquired MDR/XDR Pseudomonas aeruginosa infections

Abstract
Background: P. aeruginosa is a worrisome multidrug (MDR) or even extensively drug-resistant (XDR) nosocomial pathogen. Ceftolozane/tazobactam(C/T) and ceftazidime/avibactam (CAZ/AVI), novel combinations, were recently approved for the treatment of MDR Gram-negative pathogens. Objective: To assess the in vitro activity of C/T & CAZ/AVI and against MDR/XDR P. aeruginosa isolates , detect the synergi...
Keywords
Ceftazidime/avibactam
Aztreonam
Ceftazidime
Pseudomonas aeruginosa
Medicine
Microbiology
Avibactam
Biology
Bacteria
Genetics
Sustainable Development Goals (SDG)
Good health and well-being



Ceftolozane-tazobactam, ceftazidime-avibactam and ceftazidime-avibactam plus aztreonam combination: Upcoming hope for hospital-acquired MDR/XDR Pseudomonas aeruginosa infections

Ceftolozane-tazobactam, ceftazidime-avibactam and ceftazidime-avibactam plus aztreonam combination: Upcoming hope for hospital-acquired MDR/XDR Pseudomonas aeruginosa infections

Abstract
Background: P. aeruginosa is a worrisome multidrug (MDR) or even extensively drug-resistant (XDR) nosocomial pathogen. Ceftolozane/tazobactam(C/T) and ceftazidime/avibactam (CAZ/AVI), novel combinations, were recently approved for the treatment of MDR Gram-negative pathogens. Objective: To assess the in vitro activity of C/T & CAZ/AVI and against MDR/XDR P. aeruginosa isolates , detect the synergi...
Keywords
Ceftazidime/avibactam
Aztreonam
Ceftazidime
Pseudomonas aeruginosa
Medicine
Microbiology
Avibactam
Biology
Bacteria
Genetics
Sustainable Development Goals (SDG)
Good health and well-being