Silica sulfuric acid / ethylene glycol: An Efficient Eco-friendly Catalyst for One-pot Synthesis of Tricyclic and Tetarcyclic Dihydropyrimidine Derivatives.

Nagwa Abdelazeem, Wahid Basyouni, Samir Abbas, Khairy El-Bayouki, Mohamed El-kady

Citations:

4

References:

18

Abstract

A SIMPLE and efficient eco-friendly chemical method was developed for the synthesis of series of tricyclic and tetarcyclic dihydropyrimidine derivatives in excellent yields using a one-pot, multi-component reaction in the presence of catalyst silica sulfuric acid / ethylene glycol.Tricyclic dihydropyrimidine derivatives (benzo[4,5]imidazo[1,2-a] pyrimidines derivatives) were synthesized in high yi...

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Keywords

Chemistry

Sulfuric acid

Catalysis

Ethylene glycol

Ethyl acetoacetate

Cyanoacetamide

Tricyclic

Organic chemistry

Environmentally friendly

Biginelli reaction

Pyrimidine

Combinatorial chemistry

Stereochemistry

Ecology

Biology

Sustainable Development Goals (SDG)

Responsible consumption and production

2019

Article

Open Access

Institution

Organometallic and Organometalloid Chemistry Department, National Research Centre, Cairo, Egypt.,

Chemistry Department, Faculty of Science, Ain Shams University

2-Y Citation Average

0.712

DOI

https://doi.org/10.21608/ejchem.2019.13142.1827

Language

en

Country

Egypt