Background: Acute lung injury (ALI) is one of the most dangerous illnesses affecting the lungs. During the COVID-19 pandemic, many patients developed ALI and ultimately lung failure. Local exposure to lipopolysaccharide (LPS) is associated with cytokine production by the lung resulting in the infiltration of neutrophils and other mononuclear cells. Lactoferrin (LF) is a glycoprotein that binds iro...