Synthesis of Some New Phenazine Derivatives as Antifungal Agents

References:

17

Abstract

2-Methyloxazolo[4,5-b]phenazine (2) was obtained through the cyclocondensation of 3-aminophenazin-2-ol (1) with acetic anhydride.Oxazolophenazine derivatives (3a-d) were synthesized by oxidatively adding 3-aminophenazin-2-ol (1) to aromatic aldehydes.The addition of 3-aminophenazin-2-ol (1) to activated acrolein resulted in the formation of the 2-methylene-2H-[1,4]oxazino[2,3-b]phenazine (5).Alkyl...

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Keywords

Phenazine

Antifungal

Combinatorial chemistry

Chemistry

Biology

Microbiology

Organic chemistry

Sustainable Development Goals (SDG)

Zero hunger

2023

Article

Open Access

Institution

Department of Mathematics, College of Science and Arts, Qassim University, Riyadh Al Khabra, Saudi Arabia

2-Y Citation Average

0.712

DOI

https://doi.org/10.21608/ejchem.2024.254620.8978

Language

en

Country

Saudi Arabia

Synthesis of Some New Phenazine Derivatives as Antifungal Agents

Egyptian Journal of Chemistry

Islam Ragab

References:

17

Abstract

2-Methyloxazolo[4,5-b]phenazine (2) was obtained through the cyclocondensation of 3-aminophenazin-2-ol (1) with acetic anhydride.Oxazolophenazine derivatives (3a-d) were synthesized by oxidatively adding 3-aminophenazin-2-ol (1) to aromatic aldehydes.The addition of 3-aminophenazin-2-ol (1) to activated acrolein resulted in the formation of the 2-methylene-2H-[1,4]oxazino[2,3-b]phenazine (5).Alkyl...