Study of the Biological Activity of Microwave Synthesized of some new Pyridine derivatives fused with Sulfonamide Moiety

References:

20

Abstract

Alkylation of pyridine 1a,b with 3-chloropropanol, 1,3-dichloroisopropanol, epichlorohydrin and methyl bromoacetate under microwave irradiation afforded N-(4-(5-cyano-6-(3-hydroxypropoxy)-4-(4-isopropylphenyl)pyridin-2-yl)phenyl)-4-methylbenzenesulfonamide (2a), N-(4-(5-cyano-6-(3-hydroxypropoxy)-4-(thiophen-2-yl)pyridin-2-yl)phenyl)-4-methylbenzenesulfonamide (2b), N-(4-(6-(3-chloro-2hydroxypropo...

View PDF

Keywords

Moiety

Pyridine

Sulfonamide

Microwave

Chemistry

Combinatorial chemistry

Organic chemistry

Computer science

Telecommunications

2023

Article

Open Access

Institution

Department of Mathematics, College of Science and Arts, Qassim University, Riyadh Al Khabra, Saudi Arabia,

Department of chemistry, Faculty of science, Jazan university, Saudi Arabia.

2-Y Citation Average

0.712

DOI

https://doi.org/10.21608/ejchem.2023.245709.8801

Language

cy

Country

Saudi Arabia

Study of the Biological Activity of Microwave Synthesized of some new Pyridine derivatives fused with Sulfonamide Moiety

Egyptian Journal of Chemistry

Islam Ragab, Rasha Abd El-Hady

References:

20

Abstract

Alkylation of pyridine 1a,b with 3-chloropropanol, 1,3-dichloroisopropanol, epichlorohydrin and methyl bromoacetate under microwave irradiation afforded N-(4-(5-cyano-6-(3-hydroxypropoxy)-4-(4-isopropylphenyl)pyridin-2-yl)phenyl)-4-methylbenzenesulfonamide (2a), N-(4-(5-cyano-6-(3-hydroxypropoxy)-4-(thiophen-2-yl)pyridin-2-yl)phenyl)-4-methylbenzenesulfonamide (2b), N-(4-(6-(3-chloro-2hydroxypropo...