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Synthesis and Antibacterial Evaluation of New developed 2,3-Dihydroquinazolin-4(1H)-ones
Abstract
Antibacterial agents structurally based on quinazolin-4-one pharmacophore, have been designed and synthesized.Where the targeted compounds 5a, c and 6a-c were in vitro screened against three gram positive and three gram negative bacteria strains compared to ciprofloxacin as reference drug.Most of compounds had moderate antibacterial activity while compound 5c showed the most significant activity a...
Keywords
Sustainable Development Goals (SDG)
2022
Article
Open Access
2-Y Citation Average
0.712
Language
Country
Synthesis and Antibacterial Evaluation of New developed 2,3-Dihydroquinazolin-4(1H)-ones
Abstract
Antibacterial agents structurally based on quinazolin-4-one pharmacophore, have been designed and synthesized.Where the targeted compounds 5a, c and 6a-c were in vitro screened against three gram positive and three gram negative bacteria strains compared to ciprofloxacin as reference drug.Most of compounds had moderate antibacterial activity while compound 5c showed the most significant activity a...
Keywords
Sustainable Development Goals (SDG)
2022
Article
Open Access
2-Y Citation Average
0.712
Language
Country