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Synthesis, Anticancer Activity and Molecular Docking Study of some New Thiazolo[2, 3-a]Pyrimidinedione-Based Heterocyclic Compounds
Abstract
New thiazolo[2,3-a] pyrimidinedione derivatives were synthesized by two different chemical methods.One method included the addition of a mixture of glacial acetic acid ,acetic anhydride (2 : 1), chloroacetic acid and anhydrous sodium acetate to mercapto-thieno[2,3-d]pyrimidinone derivatives 5a or 5b under reflux to give thieno[2,3-d]thiazolo[3,2-a]pyrimidinedione derivatives 6a or 6b which react w...
Keywords
2023
Article
Open Access
2-Y Citation Average
0.712
Language
Country
Synthesis, Anticancer Activity and Molecular Docking Study of some New Thiazolo[2, 3-a]Pyrimidinedione-Based Heterocyclic Compounds
Abstract
New thiazolo[2,3-a] pyrimidinedione derivatives were synthesized by two different chemical methods.One method included the addition of a mixture of glacial acetic acid ,acetic anhydride (2 : 1), chloroacetic acid and anhydrous sodium acetate to mercapto-thieno[2,3-d]pyrimidinone derivatives 5a or 5b under reflux to give thieno[2,3-d]thiazolo[3,2-a]pyrimidinedione derivatives 6a or 6b which react w...
Keywords
2023
Article
Open Access
2-Y Citation Average
0.712
Language
Country