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A Reverse phase HPLC method Development and Validation of 2,4,6 Trifluro Benzoic acid and its impurities: A Key Raw Material Used In Preparation of Anti Migraine Drug Lasmiditan Hemisuccinate

Abstract
A novel gradient reverse phase liquid chromatographic (RP-HPLC) method is developed and validated for the determination of purity of 2,4,6 Trifluro benzoic acid (TBA) in presence of its related impurities.TBA is very important key raw material used in the process development of Active Pharmaceutical Ingredient (API), Lasmiditan Hemisuccinate.The impurities formed during the synthesis of TBA will d...
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Keywords
Chromatography
Impurity
Benzoic acid
High-performance liquid chromatography
Migraine
Chemistry
Active ingredient
Raw material
Pharmacology
Drug
Medicine
Organic chemistry
Anesthesia
Sustainable Development Goals (SDG)
Good health and well-being

2023
Article

Open Access

2-Y Citation Average

0.712

Language

pdf file

A Reverse phase HPLC method Development and Validation of 2,4,6 Trifluro Benzoic acid and its impurities: A Key Raw Material Used In Preparation of Anti Migraine Drug Lasmiditan Hemisuccinate
pdf file

A Reverse phase HPLC method Development and Validation of 2,4,6 Trifluro Benzoic acid and its impurities: A Key Raw Material Used In Preparation of Anti Migraine Drug Lasmiditan Hemisuccinate

Abstract
A novel gradient reverse phase liquid chromatographic (RP-HPLC) method is developed and validated for the determination of purity of 2,4,6 Trifluro benzoic acid (TBA) in presence of its related impurities.TBA is very important key raw material used in the process development of Active Pharmaceutical Ingredient (API), Lasmiditan Hemisuccinate.The impurities formed during the synthesis of TBA will d...
View PDF
Keywords
Chromatography
Impurity
Benzoic acid
High-performance liquid chromatography
Migraine
Chemistry
Active ingredient
Raw material
Pharmacology
Drug
Medicine
Organic chemistry
Anesthesia
Sustainable Development Goals (SDG)
Good health and well-being

2023
Article

Open Access

2-Y Citation Average

0.712

Language

pdf file