Synthesis, Antitumor, Antimicrobial and Anti-Hepatities B Activities of New 3-(4-chlorophenyl)-N-(p-tolyl)acrylamide Chalcone Derivatives

Ibrahim Nassar, Adel Abdel-Rahman, Wael A. El-Sayed, heba ahmed, afrah sharaf

References:

42

Abstract

New substituted pyrimidine, pyrazole, pyridine and pyrrole derivatives were synthesized from an unsaturated arylacetylmine key derivative via cyclization reaction with the suitable corresponding reagent and their structures were characterized by elemental and spectral analyses.The synthesised compounds' anticancer, antibacterial, and anti-Hepatitis B efficacy was investigated against a variety of ...

View PDF

Keywords

Chalcone

Antimicrobial

Acrylamide

Chemistry

Stereochemistry

Traditional medicine

Combinatorial chemistry

Medicinal chemistry

Organic chemistry

Medicine

Monomer

Polymer

2023

Article

Open Access

Institution

Department of Chemistry, Faculty of Specific Education, Ain Shams University, Abassia, Cairo, Egypt,

Chemistry Department, Faculty of Science, Menofia University, Shbien El-Kom, Egypt,

Department of Chemistry, College of Science, Qassim University, Buraydah, Saudi Arabia,

Photochemistry Department, National Research Centre, Dokki, Cairo, Egypt,

Department of Chemistry, College of Science, Jazan University, Kingdom of Saudi Arabia

2-Y Citation Average

0.712

DOI

https://doi.org/10.21608/ejchem.2023.172380.7187

Language

en

Country

Egypt,

Saudi Arabia