The most catastrophic problem that affects living standards is viral infections.This work aims to discover and evaluate new antiviral agents from marine sources.Antiviral activities of n-hexane, dichloromethane, ethyl acetate, and butanol fractions of octocoralNephtheasp. were examined in vitro against Herpes simplex type I (HSV-1) and Coxsackie B4 (CoxB4) viruses using MTT assay.n-hexane fraction...