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Geometrical and Topological Descriptors for Activities Modeling of some Potent Inhibitors against Mycobacterium Tuberculosis: A Genetic Functional Approach

Abstract
I MPROVEMENT on more potent anti-tuberculosis agents is as a result of emergence of multi-drug resistant strains of M. tuberculosis.Syntheses of novel compounds are usually carried out via trial approach with lots of errors which is time consuming and expensive.QSAR is a theoretical approach, which has the potential to reduce the aforementioned problem in discovering new potent drugs against M. tu...
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Keywords
Quantitative structure–activity relationship
Robustness (evolution)
Correlation coefficient
Mycobacterium tuberculosis
Applicability domain
Multivariate statistics
Biological system
Molecular descriptor
Mathematics
Computer science
Computational biology
Tuberculosis
Machine learning
Chemistry
Biology
Medicine
Pathology
Biochemistry
Gene
Sustainable Development Goals (SDG)
Good health and well-being

2019
Article

Open Access

2-Y Citation Average

0.712

Language
Country

pdf file

Geometrical and Topological Descriptors for Activities Modeling of some Potent Inhibitors against Mycobacterium Tuberculosis: A Genetic Functional Approach
pdf file

Geometrical and Topological Descriptors for Activities Modeling of some Potent Inhibitors against Mycobacterium Tuberculosis: A Genetic Functional Approach

Abstract
I MPROVEMENT on more potent anti-tuberculosis agents is as a result of emergence of multi-drug resistant strains of M. tuberculosis.Syntheses of novel compounds are usually carried out via trial approach with lots of errors which is time consuming and expensive.QSAR is a theoretical approach, which has the potential to reduce the aforementioned problem in discovering new potent drugs against M. tu...
View PDF
Keywords
Quantitative structure–activity relationship
Robustness (evolution)
Correlation coefficient
Mycobacterium tuberculosis
Applicability domain
Multivariate statistics
Biological system
Molecular descriptor
Mathematics
Computer science
Computational biology
Tuberculosis
Machine learning
Chemistry
Biology
Medicine
Pathology
Biochemistry
Gene
Sustainable Development Goals (SDG)
Good health and well-being

2019
Article

Open Access

2-Y Citation Average

0.712

Language
Country

pdf file