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In Silico and In Vitro Anticoagulant Activity Detection of Quercetin, Rutin, and Troxerutin as New Potential Inhibitors of Factor Xa

Abstract
Factor Xa is an important target for the development of new anticoagulants.The present study aims to examine the effect of three compounds (Quercetin and its derivatives Rutin and Troxerutin) in comparison with Rivaroxaban on activated Human Clotting factor X (PDB ID: 2w26).Molecular docking was performed using iGemDock v2.1 software to predict their antiactivating factor X activity and Autodock v...
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Keywords
Rutin
In silico
Quercetin
Pharmacology
Chemistry
In vitro
Traditional medicine
Biochemistry
Medicine
Gene
Antioxidant


pdf file

In Silico and In Vitro Anticoagulant Activity Detection of Quercetin, Rutin, and Troxerutin as New Potential Inhibitors of Factor Xa
pdf file

In Silico and In Vitro Anticoagulant Activity Detection of Quercetin, Rutin, and Troxerutin as New Potential Inhibitors of Factor Xa

Abstract
Factor Xa is an important target for the development of new anticoagulants.The present study aims to examine the effect of three compounds (Quercetin and its derivatives Rutin and Troxerutin) in comparison with Rivaroxaban on activated Human Clotting factor X (PDB ID: 2w26).Molecular docking was performed using iGemDock v2.1 software to predict their antiactivating factor X activity and Autodock v...
View PDF
Keywords
Rutin
In silico
Quercetin
Pharmacology
Chemistry
In vitro
Traditional medicine
Biochemistry
Medicine
Gene
Antioxidant


pdf file