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Deterioration of Cytochrome C Content and Mitochondrial Dysfunction in Brain of Male Rats after Sub-Chronic Exposure to Thiamethoxam and Protective Role of N- Acetylcysteine

Abstract
Mitochondria sustain healthy brain function. Herein we aimed to evaluate the thiamethoxam (MX) effect on the rat brain mitochondria in addition to the protective role of N-acetylcysteine (NAC) against MX harmful effects. Thiamethoxam was administered orally with five doses each week for 28 days to male albino rats at 1/50 of the LD50 (31.26 mg/kg bw). The results demonstrated that the thiamethoxam...
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Keywords
Thiamethoxam
Acetylcysteine
Mitochondrion
Medicine
Pharmacology
Chemistry
Toxicology
Biology
Biochemistry
Antioxidant
Pesticide
Imidacloprid
Agronomy
Sustainable Development Goals (SDG)
Zero hunger


pdf file

Deterioration of Cytochrome C Content and Mitochondrial Dysfunction in Brain of Male Rats after Sub-Chronic Exposure to Thiamethoxam and Protective Role of N- Acetylcysteine
pdf file

Deterioration of Cytochrome C Content and Mitochondrial Dysfunction in Brain of Male Rats after Sub-Chronic Exposure to Thiamethoxam and Protective Role of N- Acetylcysteine

Abstract
Mitochondria sustain healthy brain function. Herein we aimed to evaluate the thiamethoxam (MX) effect on the rat brain mitochondria in addition to the protective role of N-acetylcysteine (NAC) against MX harmful effects. Thiamethoxam was administered orally with five doses each week for 28 days to male albino rats at 1/50 of the LD50 (31.26 mg/kg bw). The results demonstrated that the thiamethoxam...
View PDF
Keywords
Thiamethoxam
Acetylcysteine
Mitochondrion
Medicine
Pharmacology
Chemistry
Toxicology
Biology
Biochemistry
Antioxidant
Pesticide
Imidacloprid
Agronomy
Sustainable Development Goals (SDG)
Zero hunger


pdf file