Role of Glutathione-S-Transferase M1 (GSTM1) and T1 (GSTT1) Genes on Aluminum Concentration and Oxidative Markers among Autistic Children

Sara Said, Gehan Moubarz, Hala Awadalla, Noha Hegazy, Nevin Sharaf, Ahmed Abdel Gawad, Amal Elsaied, Mohamed Elkhafif

Citations:

6

References:

50

Abstract

Autism Spectrum Disorder (ASD) is considered a multifaceted neurodevelopmental disorder. The last two decades showed an increase in its prevalence until reached about 1 in 54 children. Autistic symptoms may be exacerbated when the interaction of the genetic and the environmental risk factors occur, suggesting that gene-environment interaction could be a mechanism underlying the etiology of ASD. Al...

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Keywords

Glutathione S-transferase

Transferase

Glutathione

Gene

Oxidative phosphorylation

Autism

Biology

Genetics

Biochemistry

Psychology

Enzyme

Developmental psychology

2021

Article

Open Access

Institution

Assistant researcher, Environmental and Occupational medicine, National Research Center, Giza, Egypt.,

Researcher of Clinical Genetics at Department of Children with Special Needs- National Research Centre, Giza, Egypt.,

Professor of Medical Biochemistry- Medical Science Department- Faculty of Graduate Studies and Environmental Research - Ain shams university, Cairo, Egypt.

2-Y Citation Average

0.712

DOI

https://doi.org/10.21608/ejchem.2021.94656.4464

Language

en

Country

Egypt