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Synthesis and Identification of some new Derivatives Oxazole, Thiazole and Imidazol from Acetyl Cysteine

Abstract
Some fused heterocyclic oxazoles and imidazols rings were synthesized from reaction of N-acetyl cysteine with different treatment.After thiol group protection, N-acetyl-S-ethyl cysteine (2) had been esterified to give ester 3 which cyclized to oxazole 4 with phosphorus oxychloride.N-acetyl-S-ethyl cysteine 2 were converted to acid chloride 5 with thionyle chloride.Amide 6 were synthesized from 5 w...
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Keywords
Oxazole
Thiazole
Chemistry
Amide
Ring (chemistry)
Benzoxazole
Benzimidazole
Chloride
Medicinal chemistry
Organic chemistry
Stereochemistry
Sustainable Development Goals (SDG)
Clean water and sanitation


pdf file

Synthesis and Identification of some new Derivatives Oxazole, Thiazole and Imidazol from Acetyl Cysteine
pdf file

Synthesis and Identification of some new Derivatives Oxazole, Thiazole and Imidazol from Acetyl Cysteine

Abstract
Some fused heterocyclic oxazoles and imidazols rings were synthesized from reaction of N-acetyl cysteine with different treatment.After thiol group protection, N-acetyl-S-ethyl cysteine (2) had been esterified to give ester 3 which cyclized to oxazole 4 with phosphorus oxychloride.N-acetyl-S-ethyl cysteine 2 were converted to acid chloride 5 with thionyle chloride.Amide 6 were synthesized from 5 w...
View PDF
Keywords
Oxazole
Thiazole
Chemistry
Amide
Ring (chemistry)
Benzoxazole
Benzimidazole
Chloride
Medicinal chemistry
Organic chemistry
Stereochemistry
Sustainable Development Goals (SDG)
Clean water and sanitation


pdf file