New metal ion complexes of ampicillin were synthesis by two steps, first by N-acylation with benzoyl chloride and sebacoyl chloride, In the second step, the prepared compounds were reacted with cupric ion to form Cucomplexes. FT-IR, 1 H NMR, 13 C NMR, UV-visible, CHNO-S and a theoretical study was used to distinguish the prepared complexes.The biological efficacy of synthesis compound was found mo...