Synthesis of Novel Bivalent Hydrazino-Thymohydroquinone Analogs Derived from Thymoquinone as Potential Antimicrobial Agents

Ahmed Abdelazeem, Hany Arab, Mohamed El-Badway, Yasser Mohamed

References:

17

Abstract

In our previous work, it was reported that thymoquinone (TQ) and some thymohydroquinone (THQ) derivatives were used as precursors for the synthesis of potential anticancer agents.Hence, as a part of our ongoing program in the design of biologically active compounds derived from TQ scaffold we herein investigated the synthesis of homo-and heteronuclear thymol dimers tethered through various linkers...

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Keywords

Thymoquinone

Bivalent (engine)

Antimicrobial

Chemistry

Combinatorial chemistry

Traditional medicine

Medicine

Biochemistry

Organic chemistry

Antioxidant

Metal

Sustainable Development Goals (SDG)

Good health and well-being

2021

Article

Open Access

Institution

Department of Medicinal Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt,

Department of Pharmaceutical Sciences, College of Pharmacy, Riyadh Elm University, Riyadh 11681, Saudi Arabia.,

Department of Pharmacology and Toxicology-Biochemistry division, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia,

Department of Microbiology and Immunology, Faculty of Pharmacy, University of Sadat City, 32897, Menuofia, Egypt,

Photochemistry Department, National Research Center, Dokki, Giza, 12622, Egypt.

2-Y Citation Average

0.712

DOI

https://doi.org/10.21608/ejchem.2021.74154.3743

Language

en

Country

Egypt,

Saudi Arabia