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Synthesis, Characterization, Cytotoxicity Study and Docking Studies of New Fused-pyrazoline Derivatives derived from Bis-Chalcones Against Breast Cancer cells

Abstract
Breast cancer is one of the prevalent diseases that kill millions of women worldwide.The development of resistance and side effects of chemotherapy drugs is a common obstacle in the treatment of breast cancer.Recently, the focus of drug discovery has increased toward a valuable structure known as chalcones due to their extensive bioactivity in cancer treatment.In this study, 6 chalcones and 4 fuse...
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Keywords
Chalcone
Pyrazoline
Chemistry
Docking (animal)
Cytotoxicity
Stereochemistry
Cyclohexanone
Tamoxifen
MCF-7
Breast cancer
Combinatorial chemistry
In vitro
Organic chemistry
Cancer
Biochemistry
Human breast
Medicine
Catalysis
Internal medicine
Nursing
Sustainable Development Goals (SDG)
Good health and well-being


pdf file

Synthesis, Characterization, Cytotoxicity Study and Docking Studies of New Fused-pyrazoline Derivatives derived from Bis-Chalcones Against Breast Cancer cells
pdf file

Synthesis, Characterization, Cytotoxicity Study and Docking Studies of New Fused-pyrazoline Derivatives derived from Bis-Chalcones Against Breast Cancer cells

Abstract
Breast cancer is one of the prevalent diseases that kill millions of women worldwide.The development of resistance and side effects of chemotherapy drugs is a common obstacle in the treatment of breast cancer.Recently, the focus of drug discovery has increased toward a valuable structure known as chalcones due to their extensive bioactivity in cancer treatment.In this study, 6 chalcones and 4 fuse...
View PDF
Keywords
Chalcone
Pyrazoline
Chemistry
Docking (animal)
Cytotoxicity
Stereochemistry
Cyclohexanone
Tamoxifen
MCF-7
Breast cancer
Combinatorial chemistry
In vitro
Organic chemistry
Cancer
Biochemistry
Human breast
Medicine
Catalysis
Internal medicine
Nursing
Sustainable Development Goals (SDG)
Good health and well-being


pdf file