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Histological and Immunohistochemical Study on the Effect of Cyclophosphamide in Testis of Adult Albino Rats and the possible protective role of Vitamin E and Alpha Lipoic Acid

Abstract
Background: cyclophosphamide is an immunosuppressive agent and anticancer drug in childhood and adult malignant tumors. The compounds that have antioxidant properties might improve the side effect of cyclophosphamide on spermatogenesis. The aim of the work: This study designed to evaluate the effect of cyclophosphamide in testis of adult albino rats and the possible protective role of vitamin E an...
Keywords
Cyclophosphamide
Spermatogenesis
Vitamin E
Alpha-Lipoic Acid
Internal medicine
Endocrinology
Vitamin C
Immune system
Immunohistochemistry
Proliferating cell nuclear antigen
Biology
Andrology
Medicine
Antioxidant
Immunology
Chemotherapy
Biochemistry
Oxidative stress
Sustainable Development Goals (SDG)
Good health and well-being



Histological and Immunohistochemical Study on the Effect of Cyclophosphamide in Testis of Adult Albino Rats and the possible protective role of Vitamin E and Alpha Lipoic Acid

Histological and Immunohistochemical Study on the Effect of Cyclophosphamide in Testis of Adult Albino Rats and the possible protective role of Vitamin E and Alpha Lipoic Acid

Abstract
Background: cyclophosphamide is an immunosuppressive agent and anticancer drug in childhood and adult malignant tumors. The compounds that have antioxidant properties might improve the side effect of cyclophosphamide on spermatogenesis. The aim of the work: This study designed to evaluate the effect of cyclophosphamide in testis of adult albino rats and the possible protective role of vitamin E an...
Keywords
Cyclophosphamide
Spermatogenesis
Vitamin E
Alpha-Lipoic Acid
Internal medicine
Endocrinology
Vitamin C
Immune system
Immunohistochemistry
Proliferating cell nuclear antigen
Biology
Andrology
Medicine
Antioxidant
Immunology
Chemotherapy
Biochemistry
Oxidative stress
Sustainable Development Goals (SDG)
Good health and well-being