New simple sensitive spectrophotometric methods are developed for the estimation of Sulfadoxine (SFD) in pure and pharmaceutical formulations.The first method includes a conversion primary amine to azo-dye by reacting sulfadoxine with sodium nitrite and hydrochloric acid followed by coupling with4-methoxyphenol in alkaline medium to obtain a stable reddish-orange colored dye at λmax495nm.Concentra...