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Synthesis and biological activity of a new class of enaminonitrile pyrazole

Abstract
The present work illustrates the treatment of 5-amino-1,3-diphenyl-1H-pyrazole-4-carbonitrile (1) with maleic, phthalic anhydrides, acetyl chloride, and benzene sulfonyl chloride to afford the pyrazole derivatives 2-5. The treatment of pyrazole derivative 1 with some active methylene reagents namely: malononitrile, cyanoacetamide, ethyl acetoacetate afforded the pyrazolopyridine 6-9. Reaction of c...
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Keywords
Pyrazole
Class (philosophy)
Computational biology
Combinatorial chemistry
Biology
Computer science
Chemistry
Stereochemistry
Artificial intelligence
Sustainable Development Goals (SDG)
Clean water and sanitation


pdf file

Synthesis and biological activity of a new class of enaminonitrile pyrazole
pdf file

Synthesis and biological activity of a new class of enaminonitrile pyrazole

Abstract
The present work illustrates the treatment of 5-amino-1,3-diphenyl-1H-pyrazole-4-carbonitrile (1) with maleic, phthalic anhydrides, acetyl chloride, and benzene sulfonyl chloride to afford the pyrazole derivatives 2-5. The treatment of pyrazole derivative 1 with some active methylene reagents namely: malononitrile, cyanoacetamide, ethyl acetoacetate afforded the pyrazolopyridine 6-9. Reaction of c...
View PDF
Keywords
Pyrazole
Class (philosophy)
Computational biology
Combinatorial chemistry
Biology
Computer science
Chemistry
Stereochemistry
Artificial intelligence
Sustainable Development Goals (SDG)
Clean water and sanitation


pdf file