Polycholorinated dibenzo-p-dioxins (PCCDs) are widespread, persistent, and highly toxic environmental pollutants.2,3,7,8-Tetrachlorodibenzo-P-dioxin (TCDD) is the most toxic congener among PCDDs and the most thoroughly investigated model compound of this chemical class.Typical features of TCDD induced lethality are feed refusal, body weight loss, and exhaustion of energy stores, all of which are m...