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Synthesis of Arylated 1,3,5-triphenyl Pyrazoline Derivatives by Suzuki-Miyaura Reactions With Antimicrobial Evaluation

Abstract
The first palladium -catalyzed coupling reactions of 1,3,5-triphenyl pyrazoline are reported.The Suzuki-Miyaura reaction of 3-(4-bromophenyl)-1,5-diphenyl pyrazoline with one equivalent of arylboronic acids afforded 3-(biphenyl)-1,5-diphenyl pyrazoline in 53-78 % yield.While the Suzuki-Miyaura reactions of 3,5-bis(4bromophenyl)-1-phenyl pyrazoline with two equivalent of arylboronic acids gave 3,5-...
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Keywords
Antimicrobial
Chemistry
Pyrazoline
Organic chemistry
Combinatorial chemistry
Sustainable Development Goals (SDG)
Clean water and sanitation


pdf file

Synthesis of Arylated 1,3,5-triphenyl Pyrazoline Derivatives by Suzuki-Miyaura Reactions With Antimicrobial Evaluation
pdf file

Synthesis of Arylated 1,3,5-triphenyl Pyrazoline Derivatives by Suzuki-Miyaura Reactions With Antimicrobial Evaluation

Abstract
The first palladium -catalyzed coupling reactions of 1,3,5-triphenyl pyrazoline are reported.The Suzuki-Miyaura reaction of 3-(4-bromophenyl)-1,5-diphenyl pyrazoline with one equivalent of arylboronic acids afforded 3-(biphenyl)-1,5-diphenyl pyrazoline in 53-78 % yield.While the Suzuki-Miyaura reactions of 3,5-bis(4bromophenyl)-1-phenyl pyrazoline with two equivalent of arylboronic acids gave 3,5-...
View PDF
Keywords
Antimicrobial
Chemistry
Pyrazoline
Organic chemistry
Combinatorial chemistry
Sustainable Development Goals (SDG)
Clean water and sanitation


pdf file