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Effect of Tadalafil on Apoptosis and Proliferation in Urinary Bladder Mucosa after Chemically Induced Haemorrhagic Cystitis; A Histological and Immunohistochemical Study
Abstract
Introduction:Haemorrhagic cystitis (HC) can be chemically induced by cyclophosphamide (CYP) injection; it is mainly used as an immunosuppressive and antineoplastic drug.Tadalafil (TAD) a phosphodiesterase type-5 inhibitor has vasodilator, anti-inflammatory and anti-apoptotic effects.It is mainly used for the treatment of erectile dysfunction and pulmonary arterial hypertension.Aim of the Work: Thi...
Keywords
Sustainable Development Goals (SDG)
2021
Article
Open Access
Publisher
2-Y Citation Average
0.158
Language
Country
Effect of Tadalafil on Apoptosis and Proliferation in Urinary Bladder Mucosa after Chemically Induced Haemorrhagic Cystitis; A Histological and Immunohistochemical Study
Abstract
Introduction:Haemorrhagic cystitis (HC) can be chemically induced by cyclophosphamide (CYP) injection; it is mainly used as an immunosuppressive and antineoplastic drug.Tadalafil (TAD) a phosphodiesterase type-5 inhibitor has vasodilator, anti-inflammatory and anti-apoptotic effects.It is mainly used for the treatment of erectile dysfunction and pulmonary arterial hypertension.Aim of the Work: Thi...
Keywords
Sustainable Development Goals (SDG)
2021
Article
Open Access
Publisher
2-Y Citation Average
0.158
Language
Country