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Synthesis of New Pyrazolones and Fused Pyrazole Derivatives as Antimicrobial Agents

Abstract
SOME new pyrazolone and fused pyrazole derivatives start ……from enaminone-type precursor. This approach constitutes a novel and advantageous alternative for the synthesis of the target heterocycles. Thus, the reaction of pyrazolone 1 and DMFDMA afforded 4-(dimeth-ylamino)methylidenepyrazol-3-one (2). Enaminone 2 was utilized as a key intermediate for the synthesis of new pyrazolones 8, 9, 12, and ...
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Keywords
Pyrazolones
Pyrazolone
Pyrazole
Antimicrobial
Chemistry
Adduct
Combinatorial chemistry
Medicinal chemistry
Organic chemistry


pdf file

Synthesis of New Pyrazolones and Fused Pyrazole Derivatives as Antimicrobial Agents
pdf file

Synthesis of New Pyrazolones and Fused Pyrazole Derivatives as Antimicrobial Agents

Abstract
SOME new pyrazolone and fused pyrazole derivatives start ……from enaminone-type precursor. This approach constitutes a novel and advantageous alternative for the synthesis of the target heterocycles. Thus, the reaction of pyrazolone 1 and DMFDMA afforded 4-(dimeth-ylamino)methylidenepyrazol-3-one (2). Enaminone 2 was utilized as a key intermediate for the synthesis of new pyrazolones 8, 9, 12, and ...
View PDF
Keywords
Pyrazolones
Pyrazolone
Pyrazole
Antimicrobial
Chemistry
Adduct
Combinatorial chemistry
Medicinal chemistry
Organic chemistry


pdf file