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Synthesis of New Substituted Purines and [1,2,4] Triazolo- [3,4-i]purine Derivatives

Abstract
REATMENT of the 6-hydrazinopurine derivative 2a with. is …….othiocyanates followed by chloroacetyl chloride afforded, the1,3-thiazolidine-2,4-dione-2-[9-aryl-9H-purin-6-yl] hydrazones (5).Moreover, the 2-substituted [1,2,4]triazolo[3,4-i]purines 9 and 10 were synthesized by reacting 2a with aldoses and cyclizing the obtained product.
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Keywords
Purine metabolism
Purine
Chemistry
Stereochemistry
Combinatorial chemistry
Organic chemistry
Enzyme

2013
Article

Open Access


pdf file

Synthesis of New Substituted Purines and [1,2,4] Triazolo- [3,4-i]purine Derivatives
pdf file

Synthesis of New Substituted Purines and [1,2,4] Triazolo- [3,4-i]purine Derivatives

Abstract
REATMENT of the 6-hydrazinopurine derivative 2a with. is …….othiocyanates followed by chloroacetyl chloride afforded, the1,3-thiazolidine-2,4-dione-2-[9-aryl-9H-purin-6-yl] hydrazones (5).Moreover, the 2-substituted [1,2,4]triazolo[3,4-i]purines 9 and 10 were synthesized by reacting 2a with aldoses and cyclizing the obtained product.
View PDF
Keywords
Purine metabolism
Purine
Chemistry
Stereochemistry
Combinatorial chemistry
Organic chemistry
Enzyme

2013
Article

Open Access


pdf file