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New Barbiturate Derivatives as potent in vitro α-Glucosidase Inhibitors

Abstract
A series of new Schiff base derivatives were synthesized by reaction barbiturate derivatives (barbital and phenobarbital) with some aromatic aldehydes.Barbital and phenobarbital were treated with formaldehyde in ethanol as solvent to produce a and b.Then reaction compounds a or b with paratoluenesulfonylchloride in DCM and presence triethylamine to form (1,3(2H,4H)-diyl)bis(methylene)bis(4-methylb...
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Keywords
Barbiturate
In vitro
Chemistry
Pharmacology
Combinatorial chemistry
Biochemistry
Biology
Sustainable Development Goals (SDG)
Clean water and sanitation


pdf file

New Barbiturate Derivatives as potent in vitro α-Glucosidase Inhibitors
pdf file

New Barbiturate Derivatives as potent in vitro α-Glucosidase Inhibitors

Abstract
A series of new Schiff base derivatives were synthesized by reaction barbiturate derivatives (barbital and phenobarbital) with some aromatic aldehydes.Barbital and phenobarbital were treated with formaldehyde in ethanol as solvent to produce a and b.Then reaction compounds a or b with paratoluenesulfonylchloride in DCM and presence triethylamine to form (1,3(2H,4H)-diyl)bis(methylene)bis(4-methylb...
View PDF
Keywords
Barbiturate
In vitro
Chemistry
Pharmacology
Combinatorial chemistry
Biochemistry
Biology
Sustainable Development Goals (SDG)
Clean water and sanitation


pdf file